Job: Director, Chemistry/Principal Investigator, Chemistry Job

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Jobing Description

Job Title:
Director, Chemistry/Principal Investigator, Chemistry

Job ID:
12654

Location:

San Diego, CA
Offsite Territory:
Full/Part Time: Full-Time

Regular/Temporary:
Regular

Category:

Research

Department:

Medicinal Chemistry - 3264


Celgene Corporation is committed to delivering innovative therapies designed to improve the lives of patients worldwide. We are a global biopharmaceutical company with operations in more than 70 countries that is helping to turn incurable cancers into chronic, manageable conditions. We are seeking talented professionals as we continue to grow and advance our efforts in oncology, hematology and immune and inflammatory disease. If you would like to join a company where you can make a difference, please consider the Celgene family.

PhD in organic or medicinal chemistry with a minimum of 15 years of directly relevant biotechnology or pharmaceutical industry experience.

Summary:

The candidate will have senior level leadership responsibility for multiple internal and/or external research programs within the Chemistry Department at Celgene's San Diego research facility. The candidate will have strong leadership and team management skills, with a demonstrated ability to coordinate and direct the efforts of multiple staff incorporating various scientific skills and disciplines. This position will report to the head of the Chemistry Department and will be a member of the Chemistry Management Team (CMT). The successful candidate will work directly with the project and ED teams, therapeutic area leadership, other research disciplines, and contract research organizations.

Qualifications:

* PhD in chemistry with a minimum of 15 years of relevant drug discovery experience.
* Recognized as leader in medicinal chemistry and the drug discovery.
* Demonstrated track record of delivery of multiple candidates into development.
* Significant project leadership experience.
* Demonstrated ability to implement project and chemistry strategies.
* In depth knowledge of multiple therapeutic areas.
* Experience in Discovery and ED stages of drug discovery.
* Extensive working knowledge of modern medicinal chemistry and drug discovery techniques (FBDD, SBDD, multi-attribute analysis, flexible resourcing models, alternative delivery systems, etc.)
* Experience with oral and non-oral small molecule discovery and development.
* Ability to manage scientific collaborations and contracted research.
* Proven written and oral communication skills.
* Effective team building and teamwork skills.
* Detail-oriented with the ability to identify and implement creative solutions.
* Ability to prioritize and manage time efficiently.
* Previous experience with supervision and mentoring of laboratory, support and scientific staff.

Technical Skills:

* Expert in medicinal chemistry and organic synthesis.
* In-depth knowledge of projects beyond own function.
* Provide in-depth analysis & interpretations of diverse experimental results.
* Generate hypotheses and make conclusions.
* Interprets contingency plans from analysis of risk and presents alternatives.
* Demonstrates independent, scientifically-directed, and innovative thinking.
* Facilitates growth of less experienced scientists.
* Keeps management abreast of current scientific thinking.
* Functional group advisor/go-to person.
* Recognized as expert in the field and serves as subject matter expert and functional group advisor on technology, methods, etc.
* Role model for scientific excellence.
* Broad understanding of drug discovery & development and the R&D process.
* Familiar with industry trends and competitors position.

Responsibilities:

* Lead multiple discovery projects in collaboration with the relevant cross functional leadership.
* Manage external collaborations and CRO's.
* Accountable for project success and deliverables.
* Has accountability for strategies and timelines.
* Interact directly with partners in chemistry, biochemistry, DMPK, toxicology and ED.
* Set objectives for and manages multiple on-going work activities of moderate to high complexity.
* Manage budget and make resource allocation decisions that affect immediate work group or department.
* Provide leadership within functional group, department and cross-functional focus teams
* Develop and mentor scientists within and beyond functional expertise.
* Functionally supervise and direct the efforts of other staff member(s), providing guidance, instruction, opportunity and coaching
* Anticipates the need for contingencies and develops alternative strategies.
* Create, implement, and communicate functional decisions and strategy.
* Represent departmental function.
* Create, implement, and prioritize innovative ideas.
* Shape culture of functional group.
* Develops others beyond functional expertise.
* Responsible for internal and external resources.
* Coordinate cross functional activities.
* Role model for scientific culture.
* Communicate and make recommendations to line management.

Other Attributes:

* Develop technical directions for projects and department.
* Acts as a resource to peers in developing new, innovative approaches to project leadership and management.
* Recognize cross-functional issues.
* Able to anticipate problems and proactively propose solutions.
* Proven track record of scientific approach to complex problem solving.
* Demonstrate in-depth, scientific-directed, innovative thinking.
* Advises on departmental goals.
* Recognizes interrelationships of facts/factors, processes, and systems.
* Recognize risk and propose contingency plans.
* Provide an example to others in terms of leadership of science and leadership of people.
* Demonstrate through personal actions a congruency between professional excellence and commitment to the entire organization/team.
* Independently (or using collaborations) develop direction for assignments.
* Proposes innovative ideas to enhance Drug Discovery processes.
* Develops constructive relationships across organization to achieve the goals of the function and the business through leadership roles on cross-functional/divisional teams.
* Communicates within the larger organization and external community.
* Provides expert guidance to multi-disciplinary teams and senior management.
* Optional experience in non-small molecule (biologics) drug discovery

Requirements & Education:

PhD in organic or medicinal chemistry with a minimum of 15 years of directly relevant biotechnology or pharmaceutical industry experience. Candidate must have demonstrated the delivery of multiple compounds into clinical development. Must be a highly flexible, results oriented, independent self-starter who enjoys working in a fast paced dynamic environment.

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.

Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authori