Pfenex Inc

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Scientist/Sr. Scientist In Vivo Pharmacology

at Pfenex Inc

Posted: 9/9/2019
Job Status: Full Time
Job Reference #: 1168621
Keywords: research, laboratory

Job Description

  • 16-Aug-2019 (PST)
  • San Diego, CA, USA
  • Full Time

Pfenex is a clinical-stage development and licensing biotechnology company focused on leveraging its Pfenex Expression Technology to improve protein therapies for unmet patient needs. Using the patented Pfenex Expression Technology platform, the Company has created an advanced pipeline of therapeutic equivalents, vaccines, biologics and biosimilars.

POSITION SUMMARY

Pfenex Target Identification & Validation Team is seeking a talented, enthusiastic, highly motivated In Vivo Pharmacologist to develop and execute relevant disease models to support preclinical research and drug discovery programs.  The successful candidate will be a strategic member of a fast-paced and collaborative research group in discovering novel therapeutics agents.  The ideal candidate will contribute extensively with hands-on In Vivo experiments and will have a future opportunity to manage 1-2 research associates to generate robust pharmacological and disease relevant biological data with Pfenex's preclinical molecules.

ESSENTIAL DUTIES AND PRIMARY RESPONSIBILITIES

  • Planning, design, and development of animal models to test the biological efficacy of therapeutic agents
  • Identify and lead external collaborations with CROs and academic institutions
  • Present findings clearly and concisely to research teams to drive direction of drug discovery projects
  • Hire, mentor, train and professional development of research associates

JOB SKILLS, ABILITIES AND QUALIFICATIONS

  • PhD in pharmacology, biology, physiology or related field in Biomedical Sciences
  • Minimum 3+ years of biotech/pharmaceutical industry experience is required
  • Hands-on expertise in dosing, blood and tissues collection
  • Extensive surgical skills in rodents with more than one therapeutic area are essential
  • Proficiency in establishing In Vivo PK/PD models is required
  • Proven track record of managing external studies with CROs and academic labs
  • Experience with isolation of primary cells and 3D cell culture models (organoids, spheroids) is a plus
  • Extensive publication record in high-impact journal is desired
  • Proficiency in Microsoft Office and GraphPad Prism
  • Excellent organizational skills, able to multi-task and excited for hands-on In Vivo laboratory research
  • Excellent oral and written communication skills
  • Must be a team player and perform at a high level in a matrixed drug discovery environment
  • Level will be commensurate with experience

Additional Information:

  • Affirmative Action and Equal Opportunity Employer (EOE)
  • No agencies or phone calls please
  • Pfenexcelebrates the diversity of life and welcomes all individuals to apply 
  • Must be legally authorized to work in the US without sponsorship